Phénibut nofène citrocard antianxiété chimique antidépresseur insomnie médicaments sédatifs
PHENIBUT
Autres noms: 4-Chlorhydrate d'acide amino-3-phénylbutyrique, Phénibut, Noofen, Citrocard
CAS: 1078-21-3
MF: C10H14ClNO2
MW: 215.68
EINECS: 214-079-6
Apparence: poudre cristalline blanche.
PHENIBUT pure substance
Utilisations: PHENIBUT est un sédatif, A un effet calmant, réduire les tensions, anxiété, améliorer le sommeil; prolonger et renforcer l'hypnose, anesthésie, antipsychotiques.
Phénibut, vendu sous les marques Noofen et Citrocard, is a central depressant which is used in Russia for a variety of indications. It has also been reported by some researchers to possess nootropic effects due to its ability to improve neurological functions, medical citation needed] but others have not observed these effects. It is generally accepted that phenibut has anxiolytic effects in both animal models and in humans.
Phenibut is chemically related to the neurotransmitter γ-aminobutyric acid (GABA). It is believed to act as a selective GABAB receptor agonist, similarly to baclofen; studies are conflicting as to whether phenibut also acts as a GABAA receptor agonist. More recently, phenibut has been found to act preferentially as a blocker of α2δ subunit-containing voltage-gated calcium channels, similarly to gabapentin and pregabalin. As such, by definition, phenibut is a gabapentinoid.
Phenibut Medical uses
Phenibut is used in Russia as a pharmaceutical drug to treat a wide range of ailments, including anxiety, depression, asthenia, insomnie, alcoholism, posttraumatic stress disorder, stuttering, and vestibular disorders, among other conditions. In many other parts of the world, phenibut is not approved for clinical use, and is instead sold as a nutritional supplement.
