Rimonabant chemical
Rimonabant SR141716 Gewichtsverlies Pharma Chemical Acomplia
Rimonabant (SR141716)
Synoniemen: BEREIKEN;RIMONABANT;RIMONABANT(BEREIKEN,SR141716);5-(4-Chloorfenyl)-1-(2,4-dichloorfenyl)-4-methyl-N-piperidinopyrazool-3-carboxamide;1H-Pyrazool-3-carboxamide, 5-(4-chloorfenyl)-1-(2,4-dichloorfenyl)-4-methyl-N-1-piperidinyl-;5-(4-Chloorfenyl)-1-(2,4-dichloorfenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide
CAS: 168273-06-1
MF: C22H21Cl3N4O
Mw: 463.79
Rimonabant hydrochloride
MF: C22H21Cl3N4O.ClH
Mw: 500.25
CAS: 158681-13-1
Rimonabant (ook bekend als SR141716; handelsnamen Acomplia, Zimulti) was een anorectisch medicijn tegen obesitas. Rimonabant is een omgekeerde agonist voor de cannabinoïdereceptor CB1 en was het eerste medicijn dat in die klasse werd goedgekeurd. Rimonabant is a diet pills developed by the French company Sanofi-Aventis and the first cannabinoid type 1 receptor (CB1) antagonist for obesity treatment by selectively blocking marijuana in the EC system (Cannabinoid-1, CB1) receptors, can significantly reduce body weight, reduce waist circumference, reduce cardiovascular disease and other risk factors, but also can improve blood lipids and insulin resistance and metabolic syndrome, especially for There is a risk of clinical obesity or heart disease.
Rimonabant Pharma materials Chemical Test Specifications (COA):
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productnaam
Productnaam
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Rimonabant
Rimonabant
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CAS
CAS-nr.
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168273-06-1
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Inpakken
Buitenste verpakking
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MFG
Productie datum
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May 14th. 2015
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EXPIRY DATE
Houdbaarheid
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May 13th. 2017
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Products Standard
Standaard aangenomen
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Enterprise-standaard
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Analysis Item
Punten van analyse
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Kwaliteitsstandaard
Specificatie
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Resultaten
Resultaten
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Assay by (HPLC)
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99%-101%
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99.43%
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Characters/appearance
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White to off White powder
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Complies
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Odor and taste
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Odorless
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Complies
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Identificatie
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Positive reaction
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Complies
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Mesh size/sieve analysis
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100% pass 80 mesh
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Complies
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Verlies bij drogen
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1% Max
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0.78%
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Water
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≤2.0%
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0.1%
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Residu bij ontsteking
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01%Max
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Complies
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Single impurity
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0.1% Max
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Complies
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Malting point
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272.25 ºC
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Complies
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Bolling point
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627 .69 ºC
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Complies
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Refractive Index
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N20O1.67
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Complies
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PH
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50-7.0
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6.5
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pK Values
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pK. 11.31(Predicted). pK„ 3. 22 (Predicted)
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Complies
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Oplosbaarheid
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Soluble in ethanol (-20 mg/ml). DMSO (25 mg/ml) .DMF (-20mg/ml). and water (< 1 mg/ml)
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Complies
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Zware metalen
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NMT 10ppm
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Complies
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Microbiological Control
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78cfu/g
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78cfu/g
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Totaal aantal plaat aantal
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1000 cfu/g Max
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Negative
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Fungi
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<100/G
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Negative
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Salmonella
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Negative
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Negative
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Coll
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negative
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negative
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Conclusie
Conclusie
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Gekwalificeerd
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